Osmosis Jones
A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
- Director: Bobby Farrelly / Peter Farrelly
- Genre:Action / Animation / Comedy / Crime / Drama / Romance / Thriller
- Runtime:92 minutes

Cast
Chris Rock : Osmosis Jones (voice)
Laurence Fishburne : Thrax (voice)
David Hyde Pierce : Drix (voice)
Brandy Norwood : Leah (voice)
Official Site:-
Frank Detorre is a slovenly zookeeper at the New England Memorial Zoo in Rhode Island. Much to the frustration of his young daughter Shane, he eats and drinks compulsively and has no regard for germs or disease. While trying to eat a hard-boiled egg it’s stolen from him by a chimpanzee. He gets it back, but not before it falls into the filth of the chimp’s habitat. When Shane is disgusted by him about to eat it he uses the “ten second rule” as a justification for the unsanitary act.
Inside Frank’s body, the story unfolds. Protagonist Osmosis Jones, a former agent of Immunity (Frank’s immune system), is a hot-tempered, adventure-seeking white blood cell. He is a rebel cop, frequently disobeying what an authority tells him to do. He grew up poor on the “South Side” of Frank and is often mocked by his fellow cops due to his rebellious nature. At the beginning of the story, he is relocated to the mouth to fight against germs entering the body via ingestion following an incident during which he induced Frank to vomit all over Shane’s teacher, which was considered a false alarm because he had been the only one to suspect an incoming pathological threat. After several newcomer Germs, believed to be gingivitis, hijack a “squad car” in the mouth, Osmosis Jones and his senior partner, who is piloting their helicopter, are pulled into the lungs by a massive yawn while in pursuit. Even after the germs evade capture and pass into “Immunity’s” jurisdiction, Osmosis disobeys direct orders and continues the pursuit on foot. The criminals escape and Osmosis accidentally triggers a major cramp in Frank’s leg.
Meanwhile, Mayor Phlegmming is preparing for re-election, campaigning with the promise of more junk food (much to the joy of the citizens in the Love Handle District). The Mayor’s reckless policies are largely responsible for Frank’s deteriorating health; but his re-election hopes are complicated by the arrival of Thrax, a deadly virus that came with the hard-boiled egg. In an attempt to cover up the severity of the situation, Phlegmming ‘tells’ Frank to take a cold-suppressant pill. The pill, nicknamed Drix (short for his brand name Drixenol), arrives in the body and covers Frank’s infected throat with a disinfectant to cover the irritation. Osmosis Jones is assigned as Drix’s partner, much to his chagrin. Eventually, they reveal Thrax’s plot to masquerade as the common cold while at the same time plotting to overheat Frank’s body, killing him from the inside. Thrax is motivated by a desire to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death within 48 hours, breaking all previous medical records. Thrax also has the ability to burn tissue and make other cells explode by infecting them with his virus, which he releases by touching them with his larger-than-average left pointer finger, which he is able to glow, to release his virus at will. Read more
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